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From | To | Subject | Date/Time | |||
Tater Bug | All | MEDICATION SAFETY INFO |
May 19, 1995 8:45 AM * |
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In the area of prescription and OTC (over the counter) medications, your doctor is provided with a system of checks and balances which is in place to insure that you are protected from adverse reactions to drugs. This system has two main components: 1) the Physician's Desk Reference (PDR) which you doctor can consult for interactions and side effects of drugs, and which exists in both hardbound and computerized form; and 2) your pharmacist, who is trained and charged by law to review prescriptions and notify your doctor of any reason why a prescription should not be filled, and to advise customers on OTC medications similarly. He/she also relies on the PDR for this information. It would seem that this system provides the public with significant protection from inappropriate drug combinations or single prescriptions, and offers the consumer the opportunity to obtain, for the asking, similar levels of safety on OTC medications. The information below, taken directly from the PDR, indicates otherwise. It seems that whether or not a product causes adverse side effects and/or has adverse interactions with other products depends upon what the manufacturer decides to say about the product. As a sample, here is some information directly from the PDR on ibuprofen. Note that all brand names listed below contain ibuprofen only. This medication is commonly used as an OTC pain killer; all versions listed are identical in chemical content and quality, and all are within the same safety range for dosage level. The only differences are brand names and what the manufacturer publishes as side effects. If you buy Nuprin, you are told that the only side effect is "fetal problems, unspecified", leading you to believe that if you are not a pregnant female, the product is completely safe. Motrin IB caplets and Ibuprohm have the same information. Midol adds the possibility of delivery problems to the list, so again only pregnant females seem to be at risk. If you buy Haltran, you are told that ibuprofen causes fetal problems plus heartburn, stomach ache, and gastrointestinal disorders; if you buy Dristan, you are told that ibuprofen causes delivery problems (the dizziness, insomnia, and nervousness listed comes from the caffeine added to counteract the effects of the antihistimine content). If you buy adult strength Advil, delivery problems and fetal harm are listed. BUT if you buy Pediaprofen, plain old Motrin, IBU, or children's Advil, you are given a list of nearly one hundred side effects, ranging from hemolytic anemia to liver failure to kidney damage to skin rash, most of which affect less that 1% of those who take it but some of which have been documented in scientific studies as affecting 9% of those who take it, and some are listed simply as "common" reactions. Figure this into the number of people who use the drug daily and you have the possibility of over nine million serious side effects per day in this country alone. I have no desire to address the pharmaceutical industry hype about being forced to list rare side effects. The problem demonstrated above is that the information contained in the PDR is not reliable, since it depends upon the manufacturer. The bottom line is that if ibuprofen causes, for example, hemolytic anemia, this fact should be listed for all ibuprofen, not just a few brands. Since it is not, and since this problem exists for virtually all medications listed in the PDR, your doctor and your pharmacist cannot rely upon the PDR for information with which to protect you from adverse drug side effects or interactions, and with several thousand new drugs entering the market every year, not even the most experienced physician can rely upon his knowledge to make up for what the PDR does not contain. Caveat Emptor. How can YOU get around this problem? Only partially...by using the PDR yourself, cross-referencing all brand names of each chemical formulation, and using all information combined to form your picture of chemical effects and interactions. Yes, to do this WELL you need to have completed medical, chiropractic, or osteopathic school or be a microbiologist, research chemist, or exceptionally well trained Ph.D. in pharmacology, plus have enough working knowledge of true scientific method (rare) to spot the bias, unsupportable conclusions, and other bull$#!+ in research reports. But anyone can learn enough from the PDR to ask further questions, and to demand complete answers from pharmaceutical companies (even though you won't get them) and from those health care professionals you pay to assist you. For those of you who are keyboard freaks, the complete PDR is available on disk from Medical Economics Data of Montvale, NJ. It makes the task of drug information search a whole lot easier than flipping all over the place in a strangely indexed book. How else can you get around this problem? Get to know the alternatives to chemical "health care". Learn what you can do yourself to reduce or eliminate your dependence on pharmaceuticals, both prescription and OTC. Learn about Chinese accupuncture, chiropractic, homeopathy, your immune system, and nutrition. Learn how your body is affected by environmental exposures, and what you can do to counteract or avoid them. Learn by networking with others who are learning. Find out how the guy or gal or family down the street or on your local BBS has been able to enjoy good health completely without pharmaceuticals for the last year or decade. Maybe you'll even become the pharmaceutical industry's worst nightmare - a non-consumer! Then you won't need that PDR any more. |
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